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Combined Small Cell Carcinoma of the Lung: Is It a Single Entity?

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Presentation on theme: "Combined Small Cell Carcinoma of the Lung: Is It a Single Entity?"— Presentation transcript:

1 Combined Small Cell Carcinoma of the Lung: Is It a Single Entity?
Xiaoliang Zhao, MM, Justine N. McCutcheon, BS, Bhaskar Kallakury, MD, Joeffrey J Chahine, MS, Drew Pratt, MD, Mark Raffeld, MD, Yulong Chen, MM, Changli Wang, MD, PhD, Giuseppe Giaccone, MD, PhD  Journal of Thoracic Oncology  Volume 13, Issue 2, Pages (February 2018) DOI: /j.jtho Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 Overall survival curves of pure versus combined SCLC (p = 0.030). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 Immunohistochemical characteristics and boundary areas of different components in four selected cases of combined SCLC. Syn, synaptophysin; TTF-1, thyroid transcription factor 1. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

4 Figure 3 (A) The number of mutations in common, unique mutations in the SCLC component and unique mutations in the NSCLC component in three cases of combined SCLC. (B) The number of gene amplifications in common, SCLC component unique amplifications and unique amplifications in the NSCLC component in three cases of combined SCLC. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

5 Supplementary Figure 1 Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

6 Supplementary Figure 2 Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions


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