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Advances in Alport Syndrome
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Alport Syndrome (AS)
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AS Is Often Undiagnosed or Misdiagnosed
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Genetic Mutations in AS
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Type IV Collagen Networks
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AS Prevalence
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Alport Nephropathy Early and Accurate Diagnosis Is Critical
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Early Diagnosis and Management of AS Can Improve Prognosis
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Current Approaches for AS
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Early Treatment With ACEI Preserves Renal Function in Children With CKD
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CKiD Study -- Proteinuria is Major Risk Factor
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Chronic Inflammation Plays a Central Role in CKD Progression
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Bardoxolone Methyl Targets the NF-κB Cascade
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Bardoxolone Methyl in Alport Syndrome CARDINAL Phase 2/3 Study Efficacy Results
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Bardoxolone Methyl in Alport Syndrome CARDINAL Phase 2/3 Study Safety Results
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Abbreviations
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Abbreviations (cont)
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