1. Creating and Entrepreneurial Eco-System in Southern Arizona Bruce A. Wright The University of Arizona EDA Regional Training Conference 2012

2. Arizona – Coming to the Game Late No State strategy for technology innovation, commercialization or entrepreneurship Lack of Legislative support for tech commercialization State Universities lacked a effective tech transfer process Limited venture capital in the state Only one business incubator in the state Start-up leaving state to find executive teams and funding

3. Adopting a Strategy Conduct statewide assessment of strengths and weakness – Flinn Foundation and Battelle Institute Build on the research strengths (core competencies)of the Universities and Research Center Develop a regional strategies/blueprints/roadmaps Target efforts toward key industries – aerospace and defense, bioscience, optics, renewable energy

4. Meeting the Challenge Adoption of a Statewide and Regional Bioscience Roadmaps Reform of UA and ASU Tech Transfer Systems – UA Tech Launch and Technopolis Expansion of Research Parks – ASU Research Park, UA Tech Park, Phoenix Bio District, UA Bio Park

5. Meeting the Challenge Establishment of university based Incubators – Technopolis at ASU, NACET at North Arizona Univ. and Arizona Center for Innovation at UA Focused Research Centers – T-Gen in Phoenix, Critical Paths Institute and Bio 5 in Tucson Reorganization of the Arizona Department of Commerce – establishment of Arizona Commerce Authority and for start-up companies

6. Southern Arizona Response Multi-dimension approach – Entrepreneurship recruitment and training – Technology commercialization – Business start-up – Capital creation – Market expansion Engaging the key players – industry, university, private sector – Bioscience Leadership Council of Southern Arizona

7. The Biosciences in Southern Arizona Oro Valley is rapidly emerging as a regional biotech center with major new and expanding facilities – Roche / Ventana Medical Systems, Sanofi, and UAs BIO5 - Oro Valley

8. The Biosciences in Southern Arizona University of Arizona, home of the BIO5 Institute, Health Sciences Center, Biosphere 2, and Tech/Bio Parks, has spun out >30 companies since 2005

9. Bio Industry --Regional Impact

10. Biosphere 2 Bio 5 Oro Valley UA Campus Agricultural Center Arizona Cancer Center Arizona Health Sciences Center Bio 5 - Main Campus UA Main Campus UA Bio Science Park UA Tech Park Innovation Park Southern Arizona Veterans Health Care System University Physicians Hospital Tucson Medical Center Critical Path Institute Carondelet Neurological Institute Arizona Center for Innovation BioIndustry Organization of Southern Arizona Canyon Ranch Institute LifeLegacy Foundation Muscular Dystrophy Association Research Corporation for Advancement of Science Research Corporation Technologies Weil Foundation Ara Parseghian Medical Research Foundation University Governed Community Asset Research Parks & Incubators Non-University Governed Community Asset Bioscience Organization/Foundation Bioscience Matrix

11. Conduct a series of self studies – Battelle Institute Southern Arizona Roadmap, OECD Study, OURP industry Analysis Adopt Economic Development Blueprint by TREO with a focus on innovation and entrepreneurship and bioscience industry development Establish world class bioscience research organizations – UA Bio 5 and Critical Paths Institute

12. Bioscience Matrix

13. Southern Arizona Assets University of Arizona – top 15 research university with strength in the bio and life sciences Presence of industry giants – Roche (Ventana Medical) and Sanofi-Aventis (Selectide) UA Tech Park – one of the top 10 research parks in US UA top rated McGuire Entrepreneurship Program

14. The Initiatives TREO adopts Economic Blueprint with focus on entrepreneurship and innovation Establishment of Desert Angels –funding for start-ups Training for entrepreneurs – Idea Funding, Start-Up Tucson, Innovation Day at UA, AZCI Mentored Launch/Commercial Reality

16. Expansion of AzCI Programs and Facilities Turning Innovation Into Business

17. Startup Workshops Discovery non-resident UA Startup Clinics Partner Workshops Startup Workshops Discovery non-resident UA Startup Clinics Partner Workshops Mentored Launch Early-stage assessment semi-resident ~ 3 months Services include: venture assessment; workshops; coaching for launch; prep for incubation; and Pitch Day Shared office space Next Step Full Incubation Mentored Launch Early-stage assessment semi-resident ~ 3 months Services include: venture assessment; workshops; coaching for launch; prep for incubation; and Pitch Day Shared office space Next Step Full Incubation Tenant Track New Graduates Transition space Discounted lab space Tenant Track New Graduates Transition space Discounted lab space Commercial Reality Full incubation support Resident ~ 24 months Services include: venture assessment and progress tracking; workshops; coaching and individual mentoring; immediate access to extended resources; tailored support through panel and brainstorm sessions; branding and launch support; pitch and presentation events. Semi-private full service office and access to wet/dry lab facilities and equipment Next Step Community Success Commercial Reality Full incubation support Resident ~ 24 months Services include: venture assessment and progress tracking; workshops; coaching and individual mentoring; immediate access to extended resources; tailored support through panel and brainstorm sessions; branding and launch support; pitch and presentation events. Semi-private full service office and access to wet/dry lab facilities and equipment Next Step Community Success AzCI: Programs

18. Founded 2003 Strong community and national partners Focus on targeted industries To date, 60 successful companies, 50% UA 2011: 19 companies, 45 jobs, $2million + LUCEOME Biotechnologies Arizona Center for Innovation

19. Arizona Bioscience Park

20. Land Uses Education University housing Research, office and commercial space Hotel Open space E UH E E RD1 RD2 H RD1 RD2 RD1

22. ESTEEM High School Excellence in Science Technology Engineering Entrepreneurship & Math

23. ESTEEM High School Dual educational pathways – technical and academic curriculum Academic programs administered by TUSD Technical/vocational programs administered by JTED Admission open to students from throughout Pima County Adult education programs Internship and work study programs link to Bio Park companies

24. Next Steps Tech Launch Arizona -- re-engineering UA tech transfer process – focus on proof of concept, licenses, patents Arizona Business Incubation Association – network of the states incubators – sharing best practices and programs Develop of the UA Assist Program – extending entrepreneurship training, business incubation services and industry cluster formation assistance to communities throughout Southern Arizona

25. 25 New Since 02 New research institutes & entities (sampling) TGen Critical Path Institute Biodesign Institute at ASU International Genomics Consortium Partnership for Personalized Medicine/ASU Center for Sustainable Health UA BIO5 Institute UA College of Medicine- Phoenix Science Foundation Arizona SABRE TGen North Institute for Advanced Health Health Transformation Institute Arizona Biomedical Collaborative Arizona Cancer Center Skin Cancer and Cancer Health Disparities Institutes Scottsdale Healthcare Virginia G. Piper/TGen Clinical Trials Program Biosphere 2

26. New Since 02 New Schools and Education Programs (sampling) NAUTeach TGen Helios Scholars Program STEM Education Center Vail Academy and High School at UA Science & Tech Park Statewide: High school-based bioscience academies Phoenix Union Bioscience High School Copper Ridge Math and Science Academy Paradise Valley STEM High School ASU Biodesign Internships UA BIO5 Internships Wildcat School Arizona Science Center Pathways Program Bisgrove Scholars Program Helios BI05 Jr. BIOTECH Project 26

27. New Since 02 New Incubators/Accelerators (sampling) Northern Arizona Center for Entrepreneurship & Technology ASU Impact Accelerator Arizona Center for Innovation Surprise TechCelerator Chandler Innovations BioAccel Gateway Community College 27

28. New Since 02 New Facilities (sampling) UA BIO5 Oro Valley UA BIO5 Institute Banner Alzheimers Institute Biodesign Institute at ASU Flagstaff Innovation Center Arizona Bioscience Park ASU ISTB 1-4 NAU Applied R&D Building Phoenix Biomedical Campus St. Josephs Neuroscience Tower Phoenix Childrens Hospital expansion Glendale Community College life sciences building Paradise Valley Community College life science building Mayo Collaborative Research Building UMC Cancer Center Diamond Childrens Medical Center SARRC Research Center (2012) 28

29. New Since 02 New or Expanded Major Companies (sampling) Banner M.D. Anderson Cancer Center Cancer Treatment Centers of America Caris Celgene Covance InNexus Roche/Ventana Medical Systems Sanofi-aventis VisionGate W.L. Gore Monsanto 29

30. Fast Growth Arizonas bioscience performance, 2002-present Jobs Firms U.S. +11% +20% U.S.Arizona +28% NIH Grants U.S. +54% Arizona +32% Arizona +65% Top-10 States +35% Source: Battelle, 2011 30