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Lisa C. Grossman, B. A. , Konstantinos G. Michalakis, M. D

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Presentation on theme: "Lisa C. Grossman, B. A. , Konstantinos G. Michalakis, M. D"— Presentation transcript:

1 The pathophysiology of ovarian hyperstimulation syndrome: an unrecognized compartment syndrome 
Lisa C. Grossman, B.A., Konstantinos G. Michalakis, M.D., Hyacinth Browne, M.D., Mark D. Payson, M.D., James H. Segars, M.D.  Fertility and Sterility  Volume 94, Issue 4, Pages (September 2010) DOI: /j.fertnstert Copyright © Terms and Conditions

2 Figure 1 Nomenclature of terms and conditions associated with increased intraabdominal pressure (IAP). Intraabdominal pressure is normally <5 mmHg. Increased IAP is defined as IAP ≥12 mmHg, and is associated with symptoms (shown in Table 1). ACSis IAP >20–25 mmHg with organ dysfunction (see Table 1) and is treated by decompression. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © Terms and Conditions

3 Figure 2 Proposed management of OHSS. Ovarian hyperstimualtion syndrome management includes evaluation of symptoms, labs, ultrasound, and possibly IAP measurement to determine the severity of the OHSS presentation and treat as indicated. Liver function tests might not be helpful in early diagnosis of OHSS, but could serve as a baseline reference in case ascites occur later or that liver function becomes impaired. It is our practice to send electrolytes before intervention, in case nausea or dehydration caused electrolyte abnormalities. CBC=complete blood count; LFT=liver function tests; LMWH=low molecular weight heparin. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © Terms and Conditions


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