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Cinacalcet-Associated Graft Dysfunction and Nephrocalcinosis in a Kidney Transplant Recipient
Luon W. Peng, DO, Joy L. Logan, MD, Sam H. James, MD, Katherine M. Scott, MD, Yeong-Hau Howard Lien, MD, PhD The American Journal of Medicine Volume 120, Issue 9, Pages e7-e9 (September 2007) DOI: /j.amjmed Copyright © 2007 Elsevier Inc. Terms and Conditions
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Figure 1 The post-transplant time course of the changes in serum Cr, Ca, P, FK506, and iPTH levels in relationship with administration of cinacalcet. The bottom black bar depicts the presence of cinacalcet and the arrowhead depicts the subtotal parathyroidectomy. All units are in mg/dL except for iPTH, which is in pg/mL, and FK506 in ng/mL. The iPTH was determined by a non-third-generation electro-chemiluminescent immunoassay (reference range pg/mL) except for that obtained on day 204, at which time a biPTH chemiluminescent assay was used (reference range 6-40 pg/mL). To convert biPTH to iPTH, we multiply by The American Journal of Medicine , e7-e9DOI: ( /j.amjmed ) Copyright © 2007 Elsevier Inc. Terms and Conditions
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Figure 2 Histopathology of renal graft biopsy with the arrows showing tubular destruction with intratubular calcium deposition (H&E, original magnification ×400). The American Journal of Medicine , e7-e9DOI: ( /j.amjmed ) Copyright © 2007 Elsevier Inc. Terms and Conditions
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