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Santhi Voora, Deborah B. Adey  American Journal of Kidney Diseases 

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Presentation on theme: "Santhi Voora, Deborah B. Adey  American Journal of Kidney Diseases "— Presentation transcript:

1 Management of Kidney Transplant Recipients by General Nephrologists: Core Curriculum 2019 
Santhi Voora, Deborah B. Adey  American Journal of Kidney Diseases  DOI: /j.ajkd Copyright © 2019 National Kidney Foundation, Inc. Terms and Conditions

2 Figure 1 Mechanisms of immunosuppression. Abbreviations: AP-1, activator protein 1; CTLA, cytotoxic T-lymphocyte–associated antigen; FTY, finglolimod; IKK, I κ B kinase; JAK3, Janus kinase 3; MAP, mitogen-activated protein; MHC, major histocompatibility complex; MPA, mycophenolic acid; NFAT, nuclear factor of activated T cells; NF-κB, nuclear factor κB; PI-3K, phosphoinositide 3-kinase; S-1-P, sphingosine-1-phosphate; TCR, T-cell receptor. Adapted from Halloran (N Engl J Med. 2004;351(26): ) with permission of the Massachusetts Medical Society; original content © 2004 Massachusetts Medical Society. American Journal of Kidney Diseases DOI: ( /j.ajkd ) Copyright © 2019 National Kidney Foundation, Inc. Terms and Conditions


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