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A novel technique for localization and excisional biopsy of small or Ill-defined pulmonary lesions  Thomas M Daniel, MD, Talissa A Altes, MD, Patrice.

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Presentation on theme: "A novel technique for localization and excisional biopsy of small or Ill-defined pulmonary lesions  Thomas M Daniel, MD, Talissa A Altes, MD, Patrice."— Presentation transcript:

1 A novel technique for localization and excisional biopsy of small or Ill-defined pulmonary lesions 
Thomas M Daniel, MD, Talissa A Altes, MD, Patrice K Rehm, MD, Mark B Williams, PhD, David R Jones, MD, Alexander V Stolin, MS, Spencer B Gay, MD  The Annals of Thoracic Surgery  Volume 77, Issue 5, Pages (May 2004) DOI: /j.athoracsur

2 Fig 1 Combined radiographs and scintigrams obtained 1 minute and 4 hours after the injection of radiotracer into the right lung of a Sprague-Dawley rat. Three rats are illustrated: one each injected with technetium 99m (Tc 99m) macroaggregated albumin (MAA), sulfur colloid, or pertechnetate (TcO4). Note the injection site diameter was the smallest for MAA and did not change appreciably after 4 hours for either MAA or sulfur colloid. For TcO4, no residual activity was seen in the injection site after 4 hours and significant uptake in gastric mucosa was also seen. It is well known that intravenous TcO4 is concentrated by gastric mucosa as demonstrated by uptake in the ectopic gastric mucosa of a Meckle's diverticulum during a Meckle's scan. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )

3 Fig 2 Computed tomographic (CT) images depicting appearance of biopsy proving (A) bronchioloalveolar cell carcinomas adenocarcinoma (patient 1) and (B) a benign nodule (patient 7) are similar, which demonstrates that, for small lung nodules, benign and malignant lesions cannot be reliably distinguished on CT. Needle tip abutting nodule (B) is illustrated immediately before the injection of 99mTc (C) MAA. (MAA = macroaggregated albumin.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )

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