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Impact of Psoriasis on Health-Related Quality of Life Decreases Over Time: An 11-Year Prospective Study  Jane Unaeze, Tamar Nijsten, Amy Murphy, Caitlin.

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Presentation on theme: "Impact of Psoriasis on Health-Related Quality of Life Decreases Over Time: An 11-Year Prospective Study  Jane Unaeze, Tamar Nijsten, Amy Murphy, Caitlin."— Presentation transcript:

1 Impact of Psoriasis on Health-Related Quality of Life Decreases Over Time: An 11-Year Prospective Study  Jane Unaeze, Tamar Nijsten, Amy Murphy, Caitlin Ravichandran, Robert S. Stern  Journal of Investigative Dermatology  Volume 126, Issue 7, Pages (July 2006) DOI: /sj.jid Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Percent of patients reporting high impact of psoriasis by IPSO item in 1993 and (a) High impact responses “extremely” and “quite a bit”. Responses to items on “feeling better after treatment” and “enjoyment of activities” were reserved. (b) HRQOL aspects without significant change in the percentage of patients reporting high impact. P>0.1. (c) HRQOL aspects with significant decrease in the percentage of patients reporting high impact of psoriasis. P<0.05. (d) HRQOL aspect with significant increase in the percentage of patients reporting high impact. P<0.05. *IPSO items used in calculating total IPSO score. Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 Distribution of the total number of HRQOL items with high impact related to psoriasis in 1993 and 2004.aResponse to each question was dichotomized into high impact versus or not (see Materials and Methods). bResponse to questions on “feeling better after treatment” and “enjoyment of activities” were reversed. Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions

4 Figure 3 Total IPSO scores grouped by levels of HRQOL impairment and year.a(Low: range 0–3; moderate: range 4–11; and severe: range 12–22. IPSO scores are based on sum of responses to 11-item Rasch version (see Materials and Methods). *P<0.001, McNemar's χ2 (1993 vs 2004). Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions


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