1. Staphylococcal Enterotoxins G and I, a Cause of Severe but Reversible Neonatal Enteropathy 
Sandhia Naik, Fabienne Smith, John Ho, Nicholas M. Croft, Paola Domizio, Elisabeth Price, Ian R. Sanderson, Nigel J. Meadows 
Clinical Gastroenterology and Hepatology 
Volume 6, Issue 2, Pages (February 2008)
DOI: /j.cgh
Copyright © 2008 AGA Institute Terms and Conditions

2. Figure 1
Infant 1: duodenal biopsy specimen. H&E staining at high power shows marked villous atrophy and a dense inflammatory infiltrate in the lamina propria. (Color version of this figure is available online at
Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh )
Copyright © 2008 AGA Institute Terms and Conditions

3. Figure 2
Infant 1: EM of duodenal biopsy specimen. EM 24,000× shows loss of microvilli, cytoplasmic vacuolation, no secretary granules, and no inclusion bodies.
Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh )
Copyright © 2008 AGA Institute Terms and Conditions

4. Figure 3
Infant 2: duodenal biopsy specimen. H&E staining at low power shows marked villous atrophy and a dense inflammatory infiltrate in the lamina propria with crypt hyperplasia. (Color version of this figure is available online at
Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh )
Copyright © 2008 AGA Institute Terms and Conditions

5. Figue 4
Infant 2: duodenal biopsy specimen. Periodic acid–Schiff staining showing abnormal/absent accumulation of brush-border membrane material. (Color version of this figure is available online at
Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh )
Copyright © 2008 AGA Institute Terms and Conditions

6. Figure 5
Infant 2: EM of duodenal biopsy specimen. EM 24,000× shows short, stunted, abnormal microvilli, dilated mitochondria, lysosymes with cellular debris, and no inclusion bodies.
Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh )
Copyright © 2008 AGA Institute Terms and Conditions

7. Figure 6
Infant 2: EM of duodenal biopsy specimen. Three months after PN and intravenous antibiotics, a return to normal microvillous architecture was seen.
Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh )
Copyright © 2008 AGA Institute Terms and Conditions