1. Volume 57, Issue 4, Pages 1484-1492 (April 2000)
Intermittent administration of parathyroid hormone (1-37) improves growth and bone mineral density in uremic rats 
Claus P. Schmitt, Silke Hessing, Jun Oh, Lutz Weber, Peter Ochlich, Dr Otto Mehls 
Kidney International 
Volume 57, Issue 4, Pages (April 2000)
DOI: /j x
Copyright © 2000 International Society of Nephrology Terms and Conditions

2. Figure 1
Length gain in uremic rats treated either with solvent, PTH(1-37) subcutaneously (30 μg/kg b.i.d. subcutaneously), 1,25(OH)2D3 (100 pmol/kg b.i.d. subcutaneously), or both (experiment 3, N = 11 per group). Data are given as mean ± SEM. The overall effects of the different treatment options were analyzed by analysis of variance, followed by Duncan's test for multiple comparisons to analyze the differences between each treatment group. The asterisk denotes significant difference versus solvent and 1,25(OH)2D3-treated animals (P < 0.05).
Kidney International  , DOI: ( /j x)
Copyright © 2000 International Society of Nephrology Terms and Conditions

3. Figure 2
X-ray analysis of the femora from uremic animals treated with solvent (upper row) PTH(1-37) (30 μg/kg b.i.d. subcutaneously, second row), 1,25(OH)2D3 (100 pmol/kg b.i.d. subcutaneously, bottom row), or both (third row, experiment 4). PTH(1-37) markedly increased bone density and cortical bone thickness.
Kidney International  , DOI: ( /j x)
Copyright © 2000 International Society of Nephrology Terms and Conditions

4. Figure 3
Increase in total bone density per volume obtained by pQCT-measurements at 6 (upper panel) and 12 mm (lower panel) distal to the knee joint space (experiment 4). The overall effects of the different treatment options were analyzed by analysis of variance, followed by Duncan's test for multiple comparisons to analyze the differences between each treatment group. The asterisk denotes significant difference vs. solvent and 1,25(OH)2D3 animals (P < 0.05). The absolute increase of bone mineral density was significant in all groups. However, the increase was significantly higher in PTH(1-37)-treated animals.
Kidney International  , DOI: ( /j x)
Copyright © 2000 International Society of Nephrology Terms and Conditions