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IL-2– and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets  Sven Létourneau, DPhil, Carsten Krieg, PhD, Giuseppe Pantaleo,

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1 IL-2– and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets 
Sven Létourneau, DPhil, Carsten Krieg, PhD, Giuseppe Pantaleo, MD, Onur Boyman, MD  Journal of Allergy and Clinical Immunology  Volume 123, Issue 4, Pages (April 2009) DOI: /j.jaci Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Effect of IL-2 on T-cell subsets. IL-2 binding to its receptor triggers the upregulation or downregulation of transcription factors, as depicted in dark green ovals; cytokine receptors, as depicted on the left side of the T cell; or effector functions, as depicted on the right side of the T cell. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions


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