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Figure 1. Radiologic and pathologic findings

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Presentation on theme: "Figure 1. Radiologic and pathologic findings"— Presentation transcript:

1 Figure 1. Radiologic and pathologic findings
Radiologic and pathologic findings (A) Axial T2-weighted image of the spinal cord. (B) Fluid-attenuated inversion recovery image of the brain. (C) The liver was dark red in color reflecting massive hemorrhagic necrosis. (D) H&E staining showed degenerative hepatocytes containing large, pink to purple intranuclear inclusion bodies (Cowdry type A) that push the cell chromatin out to the edges of the nucleus (arrows). This finding suggested herpes infection. Single hepatic cell necrosis is also shown (arrowhead). (E, F) Immunohistochemistry for herpes simplex virus type 2. Viral antigens were identified in the liver (E) and bone marrow (F). (G) H&E staining showed remarkable hemophagocytosis (arrows) within the bone marrow. Scale bars: 3 cm (C), 20 μm (D–G). H&E = hematoxylin & eosin. Kazuhiro Ikumi et al. Neurol Neuroimmunol Neuroinflamm 2016;3:e247 © 2016 American Academy of Neurology

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