1. Linking Open Drug Data (HCLSIG LODD)
Christian Bizer Freie Universität Berlin

2. Overview Linked Data Principles Linked Data Deployment on the Web
What is Linked Data?
Linked Data Deployment on the Web
What data is out there?
Linking Open Drug Data
Status and plans of the HCLSIG LODD task

3. The Classic Web Single information space, build on URIs Hyperlinks
globally unique IDs
retrieval mechanism
Hyperlinks
are the glue that holds everything together
Web Browsers
Search Engines
HTML
HTML
HTML
hyper- links
hyper- links
Which WWW2008 papers have been written by people from companies of less than 100 people?
How to overcome structure problem A B C

4. Use Semantic Web technologies to publish structured data on the Web,
Linked Data
Use Semantic Web technologies to
publish structured data on the Web,
set links between data from one data source to data within other data sources.
Thing
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Overcome seperation
typed links
typed links
typed links
typed links A B C D E

5. Data objects are identified with HTTP URIs
rdf:type
pd:cygri
foaf:Person
foaf:name
Richard Cyganiak
foaf:based_near
dbpedia:Berlin
Todo: Animation einfügen
Namespaces erklären
Retrieval erklären
RDF graph erklären
pd:cygri = dbpedia:Berlin =
Forms an RDF link between two data sources.

6. Dereferencing URIs over the Web
rdf:type
pd:cygri
foaf:Person
foaf:name
dp:Cities_in_Germany
dp:population
skos:subject
Richard Cyganiak
foaf:based_near
dbpedia:Berlin
Todo: Animation einfügen
Namespaces erklären
Retrieval erklären
RDF graph erklären

7. Dereferencing URIs over the Web
rdf:type
pd:cygri
foaf:Person
foaf:name
dp:Cities_in_Germany
dp:population
skos:subject
Richard Cyganiak
foaf:based_near
dbpedia:Berlin
skos:subject
dbpedia:Hamburg
Todo: Animation einfügen
Namespaces erklären
Retrieval erklären
RDF graph erklären
dbpedia:Muenchen
skos:subject

8. Applications What can I do with this? Linked Data Linked Data Mashups
Browsers
Linked Data Mashups
Search Engines
Thing
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Thing
typed links
typed links
typed links
typed links A B C D E

10. Falcons

11. DBpedia Mobile Geospatial entry point into the Web of Data
Starts with DBpedia, Revyu and Flickr data

12. DERI Semantic Web Pipes

13. 2. Linked Data Deployment on the Web
W3C Linking Open Data Community Effort
Bio2RDF Project

14. W3C Linking Open Data Project
Community effort to
publish existing open license datasets as Linked Data on the Web
interlink things between different data sources
Born out of the DBpedia project

15. The LOD Cloud More than 2 billion RDF triples
More than 3 million links between datasets.

16. Organizations publishing Linked Data
Universities and Research Institutes
Massachusetts Institute of Technology (USA)
University of Southampton (UK)
Freie Universität Berlin (DE)
DERI (IRE)
KMi, Open University (UK)
University of London (UK)
Universität Hannover (DE)
University of Pennsylvania (USA)
Universität Leipzig (DE)
Universität Karlsruhe (DE)
Joanneum (AT)
University of Toronto (CA)
Companies
BBC (UK)
OpenLink (UK)
Zitgist (USA)
Talis (UK)
Garlik (UK)
Mondeca (FR)
Cyc Foundation (USA)
Works without funding

17. The Bio2RDF Project Goals Participants
Make bioinformatics data available in RDF format on the Web.
Promote the linked data vision within the bioinformatics community.
Answer questions which were not possible or practical to ask before.
Participants
Université Laval, Canada
Queensland University of Technology, Australia

18. The Bio2RDF Cloud 27 data sources 260 million records
2,7 billion RDF triples

19. 3. Linking Open Drug Data HCLSIG task started October 1st, 2008
Primary Objectives
Survey publicly available data sets about drugs
Publish and interlink these data sets on the Web
Explore interesting questions that could be answered if the data sets are linked.

20. Questions that LODD might help to answer
Physicians and Pharmacists
What are alternative drugs for a given indication (disease)?
What are equivalent drugs (generic version of a brand name, or the chemical name of a active ingredient)?
Are there ongoing clinical trials for a drug?
Consumers
What background information is available about a drug?
Which alternative drugs are available?
What are the contraindications of a drug?
What are the results of clinical trials for a drug?
Pharmaceutical Companies
What are other companies with drugs in similar areas?
Which companies have a similar therapeutic focus?

21. Public Drug Data Sources
Source: Mark Sharp, et al: A Framework for Characterizing Drug Information Sources, 2008

22. esw.w3.org/topic/HCLSIG/LODD/Data/DataSetEvaluation

23. Potential Links between LODD Data Sets

24. LinkedCT.org – Linked Data Version of ClinicalTrials.gov
Total number of triples: 6,998,851
Number of Trials: 61,920
RDF links to other data sources: 177,975
Links to:
DBpedia and YAGO (from intervention and conditions)
GeoNames (from locations)
Bio2RDF.org's PubMed (from references)

25. Mashing Clinical Trials Data and DBpedia and Yago
Additional
Classifications
Multi-lingual
Labels and Abstracts

26. Mashing Clinical Trials Data and Geographic Datak
Classification of Places
Geo
Coordinates

27. LODD Participants Kristin Tolle (Microsoft) Eric Prud'hommeaux (W3C)
Don Doherty (Brainstage)
Susie Stephens (Lilly)
Bosse Anderssen (AZ)
Scott Marshall (University of Amsterdam)
Chris Bizer (Freie Universitat Berlin)
Glen Newton (National Research Council Canada)
Michel Dumontier (Carleton University)
TN Bhat (NIST)
Oktie Hassanzadeh (University of Toronto)
You?

28. Thanks!
References
Linking Open Drug Data HCLSIG Task
Linking Open Data Community Effort LinkingOpenData
Bio2RDF Project
Tutorial: How to Publish Linked Data on the Web