1. Trends in metabolite predictability in terms of key gene contributors.
Trends in metabolite predictability in terms of key gene contributors. Area plots depict the numbers of metabolites in data set 1 whose CMP scores are driven by synthesis, by degradation, or by both in relation to their association with the host state and their predictability. The width of each box corresponds to the number of metabolites associated with each host disease state (enriched in BV samples, depleted in BV samples, or neither), and the height corresponds to the number of metabolites that are well-predicted, anti-predicted, or not significantly predicted (also indicated by color). See Fig. S6 in the supplemental material for a similar plot describing metabolite prediction in data set 2.
Cecilia Noecker et al. mSystems 2016; doi: /mSystems