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Tolerance to ischemia and hypoxia is reduced in aged human myocardium

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Presentation on theme: "Tolerance to ischemia and hypoxia is reduced in aged human myocardium"— Presentation transcript:

1 Tolerance to ischemia and hypoxia is reduced in aged human myocardium
Justin Mariani, MBBSa, Ruchong Ou, MBBSa, Michael Bailey, MSc(Stats)b, Michael Rowland, MBBS, FRACSa, Phillip Nagley, DScc, Franklin Rosenfeldt, MD, FRACSa, Salvatore Pepe, PhDa  The Journal of Thoracic and Cardiovascular Surgery  Volume 120, Issue 4, Pages (October 2000) DOI: /mtc Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

2 Fig. 1 The recovery of trabecular contractile DF after 30 minutes of hypoxia (A) or simulated ischemia (B) is expressed as a percentage of pre-stress DF in 3 age groups. Panel C shows the percentage recovery of the DF achieved after simulated ischemia or hypoxia plotted against age as a linear function (n = 58, r 2 = 0.52, P = .0002). The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions


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