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complement fragments with differential ligand activities

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Presentation on theme: "complement fragments with differential ligand activities"— Presentation transcript:

1 complement fragments with differential ligand activities
Lectin Alternative MBL, Ficolin MASP Classical C3(H2O), FB, FP C3(H2O), Bb C3bBb C1q C1r, C1s FD C1INH C3 CFH, FI CFI CD46, CD55 C4,C2 C4bp C4bC2a C3b,Bb complement fragments with differential ligand activities C3 3 ACTIVATION PATHWAYS RECOGNITION EFFECTOR iC3b/C3d Ligands C3b, C4b iC3b, c3d C3b, C3c iC3b Complement Receptors (CR) CR1 CR2 CR3 CR4 CRIg Effector Cells NK cells macrophages/Kupffer Cells dendritic cells ϒ ẟ cells PMNL

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