1. Goal-Directed fluid therapy with closed-loop assistance during moderate risk surgery using noninvasive cardiac output monitoring: A pilot study 
A. Joosten, T. Huynh, K. Suehiro, C. Canales, M. Cannesson, J. Rinehart 
British Journal of Anaesthesia 
Volume 114, Issue 6, Pages (June 2015)
DOI: /bja/aev002
Copyright © 2015 The Author(s) Terms and Conditions

2. Fig 1
Graph of stroke volume, pulse pressure variation and fluid administration during a complicated case with major bleeding. This case was patient number 3. It was a redo of hip arthroplasty which was really complicated for the orthopedic surgeons. The surgical case was bleeding throughout the 5 h of the surgical case. The graph covers nearly the 5 h case during which 20 boluses of 100 ml (2000 ml) of albumin 5% was administered. As you can observed, shortly after induction, the closed-loop gives fluid until the stroke volume reaches the plateau of the Frank-Starling relationship and after delivers fluid to maintain the stroke volume constant during the case.
British Journal of Anaesthesia  , DOI: ( /bja/aev002)
Copyright © 2015 The Author(s) Terms and Conditions