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Inflammatory Bowel Disease in African American Children Compared With Other Racial/Ethnic Groups in a Multicenter Registry  Jolanda M. White, Siobhán.

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Presentation on theme: "Inflammatory Bowel Disease in African American Children Compared With Other Racial/Ethnic Groups in a Multicenter Registry  Jolanda M. White, Siobhán."— Presentation transcript:

1 Inflammatory Bowel Disease in African American Children Compared With Other Racial/Ethnic Groups in a Multicenter Registry  Jolanda M. White, Siobhán O'Connor, Harland S. Winter, Melvin B. Heyman, Barbara S. Kirschner, George D. Ferry, Stanley A. Cohen, Robert N. Baldassano, Terry Smith, Traci Clemons, Benjamin D. Gold  Clinical Gastroenterology and Hepatology  Volume 6, Issue 12, Pages (December 2008) DOI: /j.cgh Copyright © 2008 AGA Institute Terms and Conditions

2 Figure 1 Disease classification of the pediatric IBD patient cohort we analyzed comparing those AA patients with non-AA patients. Statistically significant differences were observed between AA children with Crohn's disease compared with non-AA (78% vs 59%); that is, proportionally more AA children had Crohn's disease. Differences also were significant when comparing AA with non-AA children with UC (18% vs 30%) and IC (4% vs 10%); whereas more non-AA children proportionally had UC or IC than did their AA counterparts. *P < .001; **P = .003; ***P = .024. Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh ) Copyright © 2008 AGA Institute Terms and Conditions

3 Figure 2 Gender classification of our pediatric IBD cohort comparing males with females whether AA or non-AA. There were no statistically significant differences in the gender distribution in either main racial/ethnic categories. *P < .001; **P ; ***P = .024. Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh ) Copyright © 2008 AGA Institute Terms and Conditions

4 Figure 3 The proportion of AA children versus non-AA children diagnosed after the age of 12 years by disease category (all IBD, CD, UC, or IC). Interestingly, for reasons yet to be explained, statistically more AA children were diagnosed with all IBD, UC, or IC compared with non-AA children. *P < .001; **P = .009; ***P = .010. Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh ) Copyright © 2008 AGA Institute Terms and Conditions

5 Figure 4 The proportion of AA children versus non-AA children with symptom onset after the age of 12 years by disease category (all IBD, CD, UC, or IC). In our cohort, statistically more AA children had symptom onset whether they had all IBD, CD, or UC compared with non-AA children. *P < .001; **P = .008; ***P = .005. Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh ) Copyright © 2008 AGA Institute Terms and Conditions


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