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Wei Huang, Guo-li Ming, Hongjun Song  Neuron 

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Presentation on theme: "Wei Huang, Guo-li Ming, Hongjun Song  Neuron "— Presentation transcript:

1 Experience Matters: Enrichment Remodels Synaptic Inputs to Adult-Born Neurons 
Wei Huang, Guo-li Ming, Hongjun Song  Neuron  Volume 85, Issue 4, Pages (February 2015) DOI: /j.neuron Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Experience-Dependent Regulation of Adult Hippocampal Neurogenesis (A) Summary of the connectivity changes in presynaptic innervations of adult-born neurons in the dentate gyrus. Left: Schematics showing major local (top) and distal (bottom) input origins. Right: Changes in response to enriched environment (EE) or voluntary running (Running) regimes. Up arrow represents increase; dash represents no change; multiple arrows indicate inputs that are largely undetectable under normal conditions. CA, Cornu Ammonis area; pp, perforant path; DG, dentate gyrus; M.L., molecular layer; SGZ/GCL, sub-granular zone/granule cell layer; MS/Ndb, medial septum/nucleus of diagonal band of Broca; EC, entorhinal cortex; Mamm, mammillary bodies. (B) Critical periods during adult hippocampal neurogenesis. RGL, radial glia-like neural stem cell; IPC, intermediate progenitor cell; LTP: long-term potentiation. Neuron  , DOI: ( /j.neuron ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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