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Comparable Outcomes after HLA-Matched Sibling and Alternative Donor Hematopoietic Cell Transplantation for Children with Fanconi Anemia and Severe Aplastic.

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Presentation on theme: "Comparable Outcomes after HLA-Matched Sibling and Alternative Donor Hematopoietic Cell Transplantation for Children with Fanconi Anemia and Severe Aplastic."— Presentation transcript:

1 Comparable Outcomes after HLA-Matched Sibling and Alternative Donor Hematopoietic Cell Transplantation for Children with Fanconi Anemia and Severe Aplastic Anemia  Christen L. Ebens, Todd E. DeFor, Rebecca Tryon, John E. Wagner, Margaret L. MacMillan  Biology of Blood and Marrow Transplantation  Volume 24, Issue 4, Pages (April 2018) DOI: /j.bbmt Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 MSD- and AD-HCT conditioning regimens and GVHD prophylaxis for FA-associated SAA. CY, cyclophosphamide; FLU, fludarabine; XRT, irradiation (with thymic shielding); SIRO, sirolimus. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 No difference in 5-year OS between MSD-HCT and AD-HCT.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 No difference in neutrophil or platelet count recovery between MSD-HCT and AD-HCT. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 No difference in incidence of acute or chronic GVHD between MSD-HCT and AD-HCT. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2017 The American Society for Blood and Marrow Transplantation Terms and Conditions

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