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RevAMPing Mitochondrial Shape to Live Longer

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Presentation on theme: "RevAMPing Mitochondrial Shape to Live Longer"— Presentation transcript:

1 RevAMPing Mitochondrial Shape to Live Longer
Lena Pernas, Luca Scorrano  Cell Metabolism  Volume 26, Issue 6, Pages (December 2017) DOI: /j.cmet Copyright © Terms and Conditions

2 Figure 1 Model for Longevity Mediated by Mitochondrial Fusion and Metabolic Rewiring Low energy states such as dietary restriction and AMPK activation require mitochondrial elongation by the outer mitochondrial fusion GTPase fzo-1 in peripheral tissues and a boost in fatty acid oxidation in mitochondria and peroxisomes to mediate lifespan extension. Cell Metabolism  , DOI: ( /j.cmet ) Copyright © Terms and Conditions


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