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Clinical and Molecular Factors Associated With Histologic Response to Topical Steroid Treatment in Patients With Eosinophilic Esophagitis  Swathi Eluri,

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Presentation on theme: "Clinical and Molecular Factors Associated With Histologic Response to Topical Steroid Treatment in Patients With Eosinophilic Esophagitis  Swathi Eluri,"— Presentation transcript:

1 Clinical and Molecular Factors Associated With Histologic Response to Topical Steroid Treatment in Patients With Eosinophilic Esophagitis  Swathi Eluri, Sara R. Selitsky, Irina Perjar, Johnathan Hollyfield, Renee Betancourt, Cara Randall, Spencer Rusin, John T. Woosley, Nicholas J. Shaheen, Evan S. Dellon  Clinical Gastroenterology and Hepatology  Volume 17, Issue 6, Pages e2 (May 2019) DOI: /j.cgh Copyright © 2019 AGA Institute Terms and Conditions

2 Figure 1 Gene expression in treatment responder groups. Yellow indicates higher relative expression and blue indicates lower relative expression. Gene names are listed on the right side of the figure. (A) Nonresponders defined as ≥15 eos/hpf (gray bar), and responders defined as <15 eos/hpf (black bar). (B) Nonresponders, defined by <50% decrease in baseline eos/hpf (gray bar), and responders defined as <1 eos/hpf (black bar). Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

3 Figure 2 ROC for a multivariable predictive model of complete histologic response (defined at <1 eos/hpf). The AUC is reported. Clinical Gastroenterology and Hepatology  , e2DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions


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