1. Published in Thyroid. January 2014, 24(1): 88-168. DOI: 10. 1089/thy
Published in Thyroid. January 2014, 24(1): DOI: /thy © Mary Ann Liebert, Inc.
FIG. 8.  Supply and metabolism of thyroid hormones affect negatively and positively T3-regulated genes in the brain. To construct this figure, the authors used individual reverse transcriptase quantitative polymerase chain reaction (RT-qPCR) data from T3-regulated genes to calculate the fold change relative to the wild-type (WT) values, and plotted the Log2FC (fold change) to make the results quantitatively comparable. The data were represented in a box-and-whiskers (5%–95%) plot. Statistical significance between each group and the WT was calculated by one-way ANOVA. For the positive genes, F5,537=272, p< For the negative genes, F5,400=145, p< *p<0.05; **p<0.01; ***p< Reproduced with permission from Hernandez et al. (492).