Presentation is loading. Please wait.

Presentation is loading. Please wait.

BIOTECHNOLOGY Embryonic stem cells and gene therapy GM Golden Rice.

Published byMarilyn Morgan Modified over 5 years ago

Similar presentations

Presentation on theme: "BIOTECHNOLOGY Embryonic stem cells and gene therapy GM Golden Rice."— Presentation transcript:

1 BIOTECHNOLOGY Embryonic stem cells and gene therapy GM Golden Rice.
7/1/2019 BIOTECHNOLOGY Embryonic stem cells and gene therapy GM Golden Rice. Dolly and surrogate Mom G. Podgorksi, Biol. 1010

2 Biotechnology 7/1/2019 Biotechnology Biotechnology, defined broadly, is the engineering of organisms for useful purposes. Often, biotechnology involves the creation of hybrid genes and their introduction into organisms in which some or all of the gene is not normally present. G. Podgorksi, Biol. 1010

3 Biotechnology Animal cloning GMO’s and Bioethics Gene Cloning Gene
7/1/2019 Biotechnology Animal cloning GMO’s and Bioethics Gene Cloning Gene Therapy DNA Fingerprinting G. Podgorksi, Biol. 1010

4 Why Clone Animals? Discovery Pharmaceutical production.
Biotechnology 7/1/2019 Why Clone Animals? Discovery Pharmaceutical production. Herd improvement. Human desires G. Podgorksi, Biol. 1010

5 Is Animal Cloning Ethical?
Biotechnology 7/1/2019 Is Animal Cloning Ethical? As with many important questions, the answer is beyond the scope of science. This has given rise to the field of Bioethics. G. Podgorksi, Biol. 1010

6 Biotechnology 7/1/2019 Iranian scientists recently cloned a wild sheep (mouflon) for 2 reasons: To protect food webs To protect gene stocks G. Podgorksi, Biol. 1010

7 Carbon Copy– the First Cloned Pet
Biotechnology 7/1/2019 Carbon Copy– the First Cloned Pet (Science (2002) 295:1443) Significantly, Carbon Copy is not a phenotypic carbon copy of the animal she was cloned from. G. Podgorksi, Biol. 1010

8 Biotechnology 7/1/2019 The Next Step? This is highly unlikely. Attempts at human cloning are viewed very unfavorably in the scientific community. . G. Podgorksi, Biol. 1010

9 Recombinant DNA, Gene Cloning, and Pharmaceutical Production
Biotechnology 7/1/2019 Recombinant DNA, Gene Cloning, and Pharmaceutical Production DNA can be cut at specific sequences using restriction enzymes. This creates fragments useful for gene cloning. G. Podgorksi, Biol. 1010

10 Restriction Enzymes Cut DNA Only at Particular Sequences
Biotechnology 7/1/2019 Restriction Enzymes Cut DNA Only at Particular Sequences Different restriction enzymes have different recognition sequences. This makes it possible to create a wide variety of different gene fragments G. Podgorksi, Biol. 1010

11 These Fragments Can be Joined Together in New Ways
Biotechnology 7/1/2019 These Fragments Can be Joined Together in New Ways G. Podgorksi, Biol. 1010

12 Plasmids are Used to Replicate a Recombinant DNA
Biotechnology 7/1/2019 Plasmids are Used to Replicate a Recombinant DNA Plasmids are small circles of DNA found in bacteria. Pieces of foreign DNA can be added to create a recombinant plasmid. Replication produces up to 100 copies of a recombinant plasmid in each cell. G. Podgorksi, Biol. 1010

13 Route to the Production by Bacteria of Human Insulin
Biotechnology 7/1/2019 Route to the Production by Bacteria of Human Insulin Cloning animation G. Podgorksi, Biol. 1010

14 Production of Human Insulin
Biotechnology 7/1/2019 Production of Human Insulin G. Podgorksi, Biol. 1010

15 Biotechnology Pharming 7/1/2019 The production of pharmaceuticals in animals engineered to contain a foreign, drug-producing gene. These goats contain the human gene for a clot-dissolving protein that is produced in their milk. G. Podgorksi, Biol. 1010

16 Biotechnology 7/1/2019 The Stem Cell Concept A stem cell is an undifferentiated, dividing cell that gives rise to a daughter cell like itself and a daughter cell that becomes a specialized cell type. G. Podgorksi, Biol. 1010

17 Some Thorny Ethical Questions
Biotechnology 7/1/2019 Some Thorny Ethical Questions Are these masses of cells a human? Is it ethical to harvest embryonic stem cells from “extra” embryos created during in vitro fertilization? G. Podgorksi, Biol. 1010

18 The Technology of DNA Fingerprinting
Biotechnology 7/1/2019 The Technology of DNA Fingerprinting A DNA fingerprint used in a murder case. The defendant stated that the blood on his clothing was his. What are we looking at? How was it produced? G. Podgorksi, Biol. 1010

19 Different individuals carry different alleles.
Biotechnology 7/1/2019 Different individuals carry different alleles. Most alleles useful for DNA fingerprinting differ on the basis of the number of repetitive DNA sequences they contain. G. Podgorksi, Biol. 1010

20 DNA Fingerprinting Basics
Biotechnology DNA Fingerprinting Basics 7/1/2019 If DNA is cut with a restriction enzyme that recognizes sites on either side of the region that varies, DNA fragments of different sizes will be produced. A DNA fingerprint is made by analyzing the sizes of DNA fragments produced from a number of different sites in the genome that vary in length. G. Podgorksi, Biol. 1010

21 Biotechnology 7/1/2019 Gel electrophoresis. The DNA fragments are separated on the basis of Size. The pattern of DNA bands is compared between each sample loaded on the gel. G. Podgorksi, Biol. 1010

22 Biotechnology 7/1/2019 A DNA Fingerprint When many genes are analyzed, each with many different alleles, the chance that two patterns match by coincidence is vanishingly small. DNA detective animation HGP fingerprinting page G. Podgorksi, Biol. 1010

23 Biotechnology 7/1/2019 DNA and the Law SLT 3/8/05 Some applications of DNA fingerprinting in the justice system. G. Podgorksi, Biol. 1010

24 Genetically Modified Foods
Biotechnology 7/1/2019 Genetically Modified Foods Many of our crops in the US are genetically modified. Should they be? G. Podgorksi, Biol. 1010

25 Biotechnology 7/1/2019 GM Crops are Here Today Source: Pew Initiative on Food and Biotechnology, August 2004. G. Podgorksi, Biol. 1010

26 Biotechnology 7/1/2019 Methods for Plant Genetic Engineering are Well-Developed and Similar to Those for Animals G. Podgorksi, Biol. 1010

27 Golden Rice is Modified to be Provide a Dietary Source of Vitamin A
Biotechnology 7/1/2019 Golden Rice is Modified to be Provide a Dietary Source of Vitamin A Golden rice (yellow) with standard rice (white). Worldwide, 7% of children suffer vitamin A deficiency, many of them living in regions in which rice is a staple of the diet. G. Podgorksi, Biol. 1010

28 Genetically Modified Crops
Biotechnology 7/1/2019 Genetically Modified Crops Genetically Modified Cotton (contains a bacterial gene for pest resistance) Standard Cotton G. Podgorksi, Biol. 1010

29 GMOs, Especially Outside the US, Are a Divisive Issue
Biotechnology 7/1/2019 GMOs, Especially Outside the US, Are a Divisive Issue Protesters at the 2000 Montreal World Trade Summit European sentiment G. Podgorksi, Biol. 1010

30 Biotechnology 7/1/2019 Current Concerns by Scientists Focus on Environmental, Not Health, Effects of GM Crops The jury’s still out on the magnitude of GM crop’s ecological impact, but the question is debated seriously. G. Podgorksi, Biol. 1010

31 Biotechnology 7/1/2019 Current Concerns by Scientists Focus on Environmental, Not Health, Effects of GM Crops G. Podgorksi, Biol. 1010

Download ppt "BIOTECHNOLOGY Embryonic stem cells and gene therapy GM Golden Rice."

Similar presentations

Recombinant DNA and Genetic Engineering

Recombinant DNA and Genetic Engineering
Biotechnology Cloning Genetically modified food Four hot topics in biotechnology: Stem Cells DNA Fingerprinting.

Biotechnology Cloning Genetically modified food Four hot topics in biotechnology: Stem Cells DNA Fingerprinting.
Genetic Engineering Genetic Engineers can alter the DNA code of living organisms. Selective Breeding Recombinant DNA Gel Electrophoresis Transgenic Organisms.

Genetic Engineering Genetic Engineers can alter the DNA code of living organisms. Selective Breeding Recombinant DNA Gel Electrophoresis Transgenic Organisms.
Biotechnology. Biotechnology: broadly refers to the engineering of organisms for useful purposes Often, biotechnology involves the creation of hybrid.

Biotechnology. Biotechnology: broadly refers to the engineering of organisms for useful purposes Often, biotechnology involves the creation of hybrid.
BIOTECHNOLOGY AND GENETIC ENGINEERING CRISTINA SALVADOR.

BIOTECHNOLOGY AND GENETIC ENGINEERING CRISTINA SALVADOR.
CP Biotechnology. 13.1 Biologists Manipulate DNA Scientists use biotechnology to perform practical tasks Today, we mainly manipulate the genomes of organisms.

CP Biotechnology Biologists Manipulate DNA Scientists use biotechnology to perform practical tasks Today, we mainly manipulate the genomes of organisms.
Dolly and surrogate Mom

Dolly and surrogate Mom
Genetic Engineering. We can use a process called gel electrophoresis to separate the pieces.

Genetic Engineering. We can use a process called gel electrophoresis to separate the pieces.
Biotechnology Techniques How to make Recombinant DNA Gel Electrophoresis PCR Summarize: What is this technique? Draw and label a diagram to show this technique.

Biotechnology Techniques How to make Recombinant DNA Gel Electrophoresis PCR Summarize: What is this technique? Draw and label a diagram to show this technique.
Biotechnology & Genetic Engineering Web Research An overview.

Biotechnology & Genetic Engineering Web Research An overview.
DNA Technology n Now it gets real….. O.J. Simpson capital murder case,1/95-9/95 Odds of blood on socks in bedroom not being N. Brown-Simpson’s: 8.5 billion.

DNA Technology n Now it gets real….. O.J. Simpson capital murder case,1/95-9/95 Odds of blood on socks in bedroom not being N. Brown-Simpson’s: 8.5 billion.
Chapter 20~DNA Technology & Genomics. Who am I? Recombinant DNA n Def: DNA in which genes from 2 different sources are linked n Genetic engineering:

Chapter 20~DNA Technology & Genomics. Who am I? Recombinant DNA n Def: DNA in which genes from 2 different sources are linked n Genetic engineering:
Unit 8 test Biotech study guide.

Unit 8 test Biotech study guide.
Biotechnology. Selective Breeding Nonrandom mating to select for characteristics in parents that are desired in the offspring. Eg. Breeding domestic animals,

Biotechnology. Selective Breeding Nonrandom mating to select for characteristics in parents that are desired in the offspring. Eg. Breeding domestic animals,
Chapter 13 Genetic Engineering. This genetically engineered plant Glows-in-the-Dark!

Chapter 13 Genetic Engineering. This genetically engineered plant Glows-in-the-Dark!
Biotechnology & Genethics. What can we do with Biotechnology? Genetic Screening & testing In vitro fertilization Gene therapy & new treatments Cloning.

Biotechnology & Genethics. What can we do with Biotechnology? Genetic Screening & testing In vitro fertilization Gene therapy & new treatments Cloning.
A Look at Genetic Engineering and Biotechnology.

A Look at Genetic Engineering and Biotechnology.
BIOTECHNOLOGY AND GENETIC ENGINEERING. BIOTECHNOLOGY A new field of science that uses organisms or their products to improve medicine, healthcare, and.

BIOTECHNOLOGY AND GENETIC ENGINEERING. BIOTECHNOLOGY A new field of science that uses organisms or their products to improve medicine, healthcare, and.
Genetic Engineering Genetic Engineers can alter the DNA code of living organisms. Selective Breeding Recombinant DNA PCR Gel Electrophoresis Transgenic.

Genetic Engineering Genetic Engineers can alter the DNA code of living organisms. Selective Breeding Recombinant DNA PCR Gel Electrophoresis Transgenic.
Biotechnology Dolly and surrogate Mom Genetically modified rice. Embryonic stem cells and gene therapy.

Biotechnology Dolly and surrogate Mom Genetically modified rice. Embryonic stem cells and gene therapy.

Similar presentations

Ads by Google