1. Building the foundation of the JPIAMR-VRI

2. About the JPIAMR-VRI
The JPIAMR-VRI is a virtual platform to connect research networks, research performing institutes/centres and infrastructures beyond scientific disciplines and geographic boundaries in a larger AMR One Health Global Network.

3. Why a JPIAMR - VRI?
JPIAMR, the largest joint venture in research coordination and support for AMR, recognises a need to implement a global alignment of AMR research to strengthen partnerships and avoid duplication.

4. Aim
By bridging borders and disrupting barriers between fields of research, the JPIAMR-VRI will build a virtual "corridor" facilitating alignment of strategies, and the production and sharing of scientific evidence, for developing policy and guidelines to reduce to global burden of AMR.

5. AMR Research Capacities/ Activity modules
Connecting
Bridging Partnerships, Collaborations, Forums, Workshops, Webinars.
Access
Enabling Global Access, Mappings, Frameworks, Blueprints, Expertise, Knowledge Transfers, Structuring.
Data Sharing
Online Sharing Platforms, Libraries, Catalogues.
JPIAMR-VRI
Scientific Innovation
Building Evidence in all domains of AMR, including human and animal health and the environment.
Capacity Building
Training, Virtual Education, Train the Trainers, Exchange Programs.
Awareness
Developing and Sharing research results, Promoting AMR in the Global Agenda 

6. Membership Who is the JPIAMR-VRI for?
To be discussed in the next session

7. What the JPIAMR-VRI is not.
The JPIAMR-VRI is not a funding instrument in itself.
It is not to be seen as an added infrastructure to existing country specific ones.
The JPIAMR-VRI as a global platform will not carry specific AMR Research projects on its own. The research will continue to be done by the scientific community.
It is not meant to take over other existing national or international Networks. 

8. A few of the benefits of the JPIAMR-VRI for the scientific community
Find the right people/groups to create networks, (research) consortia, research ideas and spin-off ideas, etc.
Present oneself and remain visible and detectable as an expert or entrepreneur within the AMR field.
Easy access to AMR databases, collections, biobanks, research infrastructures.
Overview of ongoing and finalised research projects (mapping).
Overview of grant schemes/funding database (globally).
Early notification of (emerging) resistance problems and novel findings.
Promote/find scientific work (publications, protocols, best practices, guidelines etc.).
Promote/find workshops, symposia, conferences, summer schools, train-the-trainer etc.
Promote/find grey literature i.e. supranational/national (e.g. NAPs) reports with policy & research agendas.
Exchange and learn from best practices, guidelines, protocols, experimental models, etc.
Invite participants, (keynote) speakers, facilitators.
Etc.

9. Governance of the JPIAMR-VRI
The JPIAMR-VRI is an entity under the JPIAMR.
The governance lies within the JPIAMR Management Board, championed by the JPIAMR-VRI Working Group lead – Canada.
The operations are supported by the JPIAMR Secretariat and coordinated by the JPIAMR-VRI Project Manager.
The Scientific Advisory Board and Steering Committee ensure oversight of positioning and alignment with the Strategic Research and Innovation Agenda.

10. The first funded Networks
In 2018, JPIAMR launched two network calls
Surveillance Networks, and
Building the Foundation of the JPIAMR-VRI.
These Networks met in Amsterdam (19-20 Feb, 2019) to explore opportunities for collaboration, synergies and to determine whether further interactions could promote and enhance their actions.
JPIAMR-VRI plans to act upon the Networks activities and recommandations.

11. Example from JPIAMR-VRI Networks
Priority Topics A B C D E F
Connecting 1
Access 2
Data Sharing 3
Activity Modules
Scientific Innovation 4
Capacity Building 5
Awareness   6
Therapeutics
Diagnostic
Surveillance
Transmission
Environment
Interventions

12. Example from JPIAMR-VRI Networks
Priority Topics A B C D E F
Connecting 1
Access 2
Data Sharing 3
Activity Modules
Scientific Innovation 4
Capacity Building 5
Awareness   6
IRAADD
Academic researchers must be helped to efficiently translate their findings into novel and useful therapeutic products.
Together with Academia, Industry & Policy, develop blueprints on research for antibiotic discovery and development
Therapeutics
Diagnostic
Surveillance
Transmission
Environment
Interventions

13. Example from JPIAMR-VRI Networks
Priority Topics A B C D E F
Connecting 1
Access 2
Data Sharing 3
Activity Modules
Scientific Innovation 4
Capacity Building 5
Awareness   6
AMR Dx Global
From the findings of the successful JPIAMR previously funded Working Group on Rapid Diagnostics
Produce a Strategic Action Plan for the establishment of a Virtual School of Diagnostics to provide training and capacity building focused on Diagnostics.
Therapeutics
Diagnostic
Surveillance
Transmission
Environment
Interventions

14. Example from JPIAMR-VRI Networks
Priority Topics A B C D E F
Connecting 1
Access 2
Data Sharing 3
Activity Modules
Scientific Innovation 4
Capacity Building 5
Awareness   6
VeRI-BEAM
Define and clarify the path and methodology to the regulatory assessment of alternative antimicrobial treatments to re-risk drug development market access and avoid pitfalls and misuse of public funding.
Identify of differentiation criteria for alternatives thereapies and open the way to the definition of these new criteria to be integrated with policy makers such as EMA or EUCAST.
Share (scientific and non-scientific) knowledge amongst AMR Research community in non-competitive matter
Therapeutics
Diagnostic
Surveillance
Transmission
Environment
Interventions

15. Example from JPIAMR-VRI Networks
Priority Topics A B C D E F
Connecting 1
Access 2
Data Sharing 3
Activity Modules
Scientific Innovation 4
Capacity Building 5
Awareness   6
NEAR AMR
Determining common capacity and capability training needs in AMR research from Europe and Africa.
Inform on preferred global surveillance data sharing platform profile of what is realistically possible within a range of existing healthcare systems from multiple geographical settings and with various resources limitations.
Therapeutics
Diagnostic
Surveillance
Transmission
Environment
Interventions

16. Work Plan Concrete outputs and activities contributing to building the JPIAMR-VRI
White/ Position paper/ Framework
Syst.Review/ Mapping
Sc. Article/ Report
Training
SOP/ Guidance document/ SRA
Database/ Platform
Gap-ONE ◉
AMRIC
AMR Dx Global
CONNECT
IRAADD
Near AMR
VeRI BEAM TT
SYNERGETIC ACTIONS: These Networks have already expressed intentions to attend each others’ meeting, and be added as Partners to each other’s Networks, collaborate with Surveillance Networks, etc.

17. Communications
JPIAMR-VRI landing page JPIAMR-VRI Networks web pages

18. Analysis of all Networks activities that will/could contribute to the foundation of the JPIAMR-VRI.
Connecting
Access
Data Sharing
Scientific Innovation
Capacity Building
Awareness   A B C D E F
Therapeutics
Diagnostics
Surveillance
Transmission
Environment
Interventions 1 2 5 3 4 6
Activity Modules
Priority topics
JPIAMR-VRI Networks

19. Example from Surveillance Networks
Priority Topics A B C D E F
Connecting 1
Access 2
Data Sharing 3
Activity Modules
Scientific Innovation 4
Capacity Building 5
Awareness   6
NETESE
Extend on WHO Tricycle surveillance pilot programs in the three sectors of One Health in all countries (especially those with limited surveillance capacities) by linking countries together to obtain yearly rates of ESBL-E.coli
Trends determinations
Inter/intra-regional comparisons
Dynamic dashboard for decision makers
Therapeutics
Diagnostic
Surveillance
Transmission
Environment
Interventions

20. Analysis of all Networks activities that will/could contribute to the foundation of the JPIAMR-VRI.
Connecting
Access
Data Sharing
Scientific Innovation
Capacity Building
Awareness   A B C D E F
Therapeutics
Diagnostics
Surveillance
Transmission
Environment
Interventions 1 2 5 3 4 6
Activity Modules
Priority topics
Early Stage Drug Accelerator
Surveillance Networks
JPIAMR-VRI Networks

21. Work Plan Concrete tasks and activities Oct2018-Apr2019 AGREEMENT
DEVELOPMENT
Agreement for PM resource
New funding program concept paper
Added MS as JPIAMR-VRI fee contributors
JPIAMR-VRI Overview document « establishing the JPIAMR-VRI »
Start of JPIAMR-VRI PM resource
Draft Terms of reference for Task Force
WORKSHOP & MEETINGS
Developped JPIAMR-VRI Membership proposal
Plan, execute, report on Networks’ Startup WS
Update draft Work Plan + M&D
Consultations w/Steering Committee
COMMUNICATIONS
Consultation w/SAB
Comunications Plan + activities table
Bilateral discussions w/ Member States
JPIAMR-VRI Generic slide deck + 1-pager + 2-pager + webpage + subpages
Discussions with Secretariat Head
Met w/GEANT to explore opportunities for digital platform

22. Work Plan Concrete tasks and activities To come Apr-Oct2019
DEVELOPMENT
MEETINGS & WORKSHOP
Finalize Membership policy
Finalize Work Plan + M&D
Bilateral contacts with individual Network coordinators to monitor activities.
Development plan draft including funding and sustainability
Participation to Networks meetings.
Task Force Needs assessment
Adapt Terms of Reference
Bilateral discussions with MS
Survey on funding programmes fesability
Reactivation of WG and create Task Force IT
Start planning the final JPIAMR-VRI Networks WS and prepare report template
Sharepoint-type drop zone for documents
Numerous representation activities
IT Infrastructure needs assessment (with RI WG)
Prepare for next MB
Activities to come >Oct2019
Monitoring of Networks and evaluate findings
Development plan
JPIAMR-VRI Network individual final reports
Final JPIAMR-VRI Networks WS
IT infrastructure
Prepare JPIAMR-VRI Launch

23. Supporting the VRI development fee