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Removing Barriers in the HCV Cascade of Care
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Program Overview
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HCV Burden of Disease
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Worldwide HCV Prevalence (2015)
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Global Annual Mortality
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Disability From Liver Disease Has Increased (2006-2016)
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Outline of HCV Long-Term Complications Natural History of Hepatitis C
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Progression to Cirrhosis
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Progression to Cirrhosis (cont)
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Extrahepatic Manifestations of HCV Infection
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Improving the HCV Cascade of Care
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WHO Vision
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HCV Cascade of Care (British Columbia, Canada)
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HCV Cascade of Care (British Columbia, Canada) (cont)
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HCV Cascade of Care (British Columbia, Canada) (cont)
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Screening Strategies
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ELISA Assays
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NAT Testing (rtPCR or TMA)
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Point-of-Care Tests
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Rapid Diagnostic Tests (RDT)
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Dried Blood Spots (DBS)
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Confirmation of Replication
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Screening Linkage to Care
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Decentralized Screening and Care
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Simplified Pretherapeutic Assessment
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EASL Recommendations on the Treatment of Hepatitis C 2018
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Treatment Monitoring
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Simplified Treatment Monitoring
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HCV Elimination Strategies
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HCV Elimination Strategies
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HCV Elimination Strategies
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Micro-Elimination Target Groups
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US Veterans
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Concluding Remarks
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Abbreviations
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Abbreviations (cont)
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