1. Maternal derivative chromosome 9 and recurrent pregnancy loss
Ling-Wei Chang, M.D., I.-Wen Lee, M.D., Pao-Lin Kuo, M.D., Long-Ching Kuan, M.D. 
Fertility and Sterility 
Volume 88, Issue 4, Pages 968.e1-968.e3 (October 2007)
DOI: /j.fertnstert
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
The karyotype and fluorescence in situ hybridization (FISH) pictures of the proband. (A) Complete karyotype of the proband. The breakpoints were located at 9p24 for both chromosomes 9. (B) Dual-color FISH analysis with 43N6 probe (9q24.3, red) and D9Z3 probe (9q12, green) showed only one signal for both probes on the der(9). (C) Fluorescence in situ hybridization analysis with probe CEP9 (9p11∼q11, red) also revealed only one signal on der(9). (D) Derivative chromosome 9 and the corresponding ideogram. There was loss of chromatin from 9p11 to 9q12 for one chromosome 9. Both chromosomes 9 of her parents had an intact heterochromatic region (from 9p11to 9q12; data not shown).
Chang. Derivative chromosome 9 and recurrent miscarriages. Fertil Steril 2007.
Fertility and Sterility  , 968.e1-968.e3DOI: ( /j.fertnstert )
Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions