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Published byDominik Janda Modified over 5 years ago
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Fibrinogen supplementation ex vivo increasesclot firmness comparable to platelet transfusion in thrombocytopenia† B. Schenk, A.K. Lindner, B. Treichl, M. Bachler, M. Hermann, O.H. Larsen, C. Fenger-Eriksen, D. Wally, H. Tauber, C. Velik-Salchner, D. Fries British Journal of Anaesthesia Volume 117, Issue 5, Pages (November 2016) DOI: /bja/aew315 Copyright © 2016 The Author(s) Terms and Conditions
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Fig 1 Effect of ex vivo fibrinogen supplementation compared with in vivo platelet transfusion on EXTEM MCF. EXTEM MCF before (baseline V1) and after platelet transfusion (baseline V2). Samples before PT were spiked with fibrinogen concentrate (equivalent to 50–400 mg kg−1 body weight). Blood samples from patients 1 h after PT (V2) were defined as baseline values. Differences from V2 are indicated as *P < 0.05, **P < 0.01, ***P < (Wilcoxon signed-rank test). Data presented as mean (sd). CI, confidence interval. British Journal of Anaesthesia , DOI: ( /bja/aew315) Copyright © 2016 The Author(s) Terms and Conditions
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