1. Parvovirus B19: Assays, Limits and the Outcome
Dr. Matthias Gessner
Plasma Control/Plasma Analytics
Baxter, Austria

5. 1.8% 3

6. + >50% pools to resolve

7. Conclusion
A limit of 105 IU/ml on the production pool results in an actual limit of 104 IU/ml due to large CV of assays based on exponential amplification
A limit of 105 IU/ml on the production pool results in an actual average load of 100 IU/ml (>90% of production pools <100 IU/ml)
Lowering the limit to 104 IU/ml would
put the actual limit to 103 IU/ml
create 50% higher workload in resolving minipools
avoid 1.8% of production pools in range of 103 IU/ml