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Comparison of ADCC by CD16V-transduced T lymphocytes and autologous NK cell. Comparison of ADCC by CD16V-transduced T lymphocytes and autologous NK cell.

Published byFrançois Mercier Modified over 5 years ago

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Presentation on theme: "Comparison of ADCC by CD16V-transduced T lymphocytes and autologous NK cell. Comparison of ADCC by CD16V-transduced T lymphocytes and autologous NK cell."— Presentation transcript:

1 Comparison of ADCC by CD16V-transduced T lymphocytes and autologous NK cell.
Comparison of ADCC by CD16V-transduced T lymphocytes and autologous NK cell. CD16V-transfected T cells and autologous NK cells (V/V) were tested against the following target cells: the CD20+ EBV-LCL (BK01/12), the HER2+ breast cancer cell line BT-474, and the EGFR+ glioblastoma cell line LN-18 in the presence of increasing concentrations of the anti-CD20 mAb rituximab, the anti-HER2 mAb trastuzumab, and the anti-EGFR mAb cetuximab, respectively. Results are expressed as percentage of specific lysis (E:T ratio 10:1, mean of triplicate). Symbols represent the mean ± SD of two (BK01/12) and three (BT-474 and LN-18) independent experiments. Jocelyn Ollier et al. ImmunoHorizons 2017;1:63-70 Copyright © 2017 The Authors

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