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Efficacy and safety of human chorionic gonadotropin for follicular phase stimulation in assisted reproduction: a systematic review and meta-analysis 

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Presentation on theme: "Efficacy and safety of human chorionic gonadotropin for follicular phase stimulation in assisted reproduction: a systematic review and meta-analysis "— Presentation transcript:

1 Efficacy and safety of human chorionic gonadotropin for follicular phase stimulation in assisted reproduction: a systematic review and meta-analysis  Miguel A. Checa, M.D., Juan José Espinós, M.D., Antonio Requena, M.D.  Fertility and Sterility  Volume 97, Issue 6, Pages e3 (June 2012) DOI: /j.fertnstert Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Effectiveness of hCG supplementation versus standard stimulation protocols for the outcome of clinical pregnancy. Fertility and Sterility  , e3DOI: ( /j.fertnstert ) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Effectiveness of hCG supplementation versus standard stimulation protocols for the outcome of retrieved metaphase II oocytes. Fertility and Sterility  , e3DOI: ( /j.fertnstert ) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

4 Figure 3 Mean differences in the FSH doses used.
Fertility and Sterility  , e3DOI: ( /j.fertnstert ) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

5 Supplemental Figure 1 Flow chart for the trial identification and selection process. Fertility and Sterility  , e3DOI: ( /j.fertnstert ) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

6 Supplemental Figure 2 Risk of bias for the 11 RCTs included in the meta-analysis. Fertility and Sterility  , e3DOI: ( /j.fertnstert ) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

7 Supplemental Figure 3 Effectiveness of hCG supplementation versus standard stimulation protocols for the outcome of live birth. Fertility and Sterility  , e3DOI: ( /j.fertnstert ) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions


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