1. Supplementary Figure 1 SK-N-SH Vehicle GW9662 Number of cells 1 2 3 5
x106
SK-N-SH 4 3
Vehicle
GW9662
Number of cells 2 1 1 2 3 5 7
Day
Supplementary Figure 1. Growth of SK-N-SH cells in the presence of absence of GW9962 (15 M). Number of viable cells were measured on the indicated.

2. Supplementary Figure 2
x105
4.5 4
3.5 3
Number of cells UT
2.5
GW9662 2
BAY
1.5
Both 1
0.5 1 2 3 4
Day
Supplementary Figure 2. No cytotoxicity effect of PPAR antagonist (GW9662) and NF- inhibitor (BAY ) in MCF10A cells. cells were subject to treated (indicated by arrow) by replacing with new media containing either GW9662 (15 M) or BAY (5 M) or both. Cells not treated with either chemicals (UT) were used as comparison. Number of viable cells were measured on 24 hour (Day 2), 48 hour (Day 3) and 72 hour (Day 4).