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SNP typing using molecular inversion probes
Hanna Edlund, Marie Allen Forensic Science International: Genetics Supplement Series Volume 1, Issue 1, Pages (August 2008) DOI: /j.fsigss Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions
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Fig. 1 Principle of padlock probes and molecular inversion probes (MIPs). (A) When using padlock probes, two allele-specific primers together with one common primer are used to be able to distinguish the genotypes. (B) MIPs have a 1-bp gap at the SNP position, which is filled by the addition of one of the four nucleotides. Forensic Science International: Genetics Supplement Series 2008 1, DOI: ( /j.fsigss ) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions
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Fig. 2 Genotypes for three different individuals for the SNP TSC (A/A, T/T, T/A). The sequence is TTCTTT/ATTCCCAT. Forensic Science International: Genetics Supplement Series 2008 1, DOI: ( /j.fsigss ) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions
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