1. Recombinant factor VIIa affects anastomotic patency of vascular grafts in a rabbit model 
C. David Mazer, MD, FRCPC, Howard Leong-Poi, MD, FRCPC, Tejinder Chhina, MD, FRCPC, Zuhair Alfardan, MD, Harry Lapierre, MD, FRCSC, Zhilan Wang, MSc, Zane S. Jackson, MD, PhD, Beiping Qiang, MD, James Mahoney, MD, FRCSC, David Latter, MD, FRCSC, Gregory M.T. Hare, MD, PhD, FRCPC, Bradley H. Strauss, MD, FRCPC, Jerome Teitel, MD, FRCPC 
The Journal of Thoracic and Cardiovascular Surgery 
Volume 142, Issue 2, Pages (August 2011)
DOI: /j.jtcvs
Copyright © 2010 The American Association for Thoracic Surgery Terms and Conditions

2. Figure 1
Vein graft patency (defined as number of grafts patent/total number of grafts∗100) was significantly reduced in a dose-dependent fashion after rFVIIa. ∗P < .05 compared with placebo. †P < .05 compared with 20 μ/kg. ‡P < .05 compared with 90 μ/kg. CI, 95% Confidence interval.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2010 The American Association for Thoracic Surgery Terms and Conditions

3. Figure 2
Plasma factor VII activity levels increased significantly after 1 of 3 doses of rFVIIa. ∗P < .05 compared with placebo at the same time point. †P < .05 compared with 20 μg/kg and 90 μg/kg at the same time point. ‡P < .05 compared with baseline value.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2010 The American Association for Thoracic Surgery Terms and Conditions