1. University of sulaimani
Tablet dosage form
Aram I. Ibrahim
University of sulaimani
College of pharmacy
Dep.of pharmaceutics

2. Introduction
tablets are solid dosage form each containing a single dose of one or more active substances.
Tablets are intended for oral administration.
Tablets can be:
Swallowed whole
Chewed
Dissolved or dispersed in water
Retained in the mouth

3. Advantages Ease of administration Stable Accurate dose
Easy to handle and transfer
Cheap

4. Disadvantages Tablets are not suitable dosage form for drugs that are:
Resist compression
Poor wetting and slow dissolution properties
Bitter-tasting drugs, drugs with an unpleasant odor.

5. Tablet formation Tablets are normally formed by powder compression.
The compression takes place in a die by the action of two punches

6. Tablet processing steps

7. Tablet press types
Single-punch press
Rotary press

10. Tablet excipients
Filler e.g., lactose, sucrose, mannitol, and calcium phosphate • Disintegrants e.g., starch and cellulose • Glidant e.g., Talc, silica • Lubricant e.g., magnesium stearate and sodium lauryl sulphate • Antiadherent talc and starch

11. Types of lubricants

12. Types of lubricants cont.

13. Types of antiadherents

14. Procedure
Mix all the required powders in a bottle and shake it for 3 minutes.
Put the powder blend in to the hopper of the tablet press machine.
Start to press the powder and collect the tablers.
Store your tablets in a tight closed container for further investigation in the next lab.

15. Recommended textbooks