1. Identification of genes with significant ASD.
Identification of genes with significant ASD. (A) Scatterplot showing the bootstrap means (x-axis) and standard deviations (y-axis) of estimated ASD. Dashed blue lines indicate the Benjamini–Hochberg–adjusted P-value of 0.05 and dashed purple lines indicate a minimum decay rate difference of Out of 8,815 genes (black), 621 (red) exhibited significant ASD. (B) Bar plots showing the number of sequencing reads assigned to BL6 (red) or SPRET (blue) alleles (y-axis) at different SNP loci (x-axis) of three time points (0, 0.5, and 1.5 h). BL6 and SPRET allele degraded faster in Armc7 and Rbak genes, respectively. (C) Scatterplot comparing allelic decay rate difference (Δλ) estimated based on Illumina sequencing data (y-axis) to that based on PacBio sequencing (x-axis) for the 25 randomly selected genes. Δλ estimated based on the two technologies was significantly correlated (rPearson=0.93, P-value<2.0×10−11).
Wei Sun et al. LSA 2018;1:e
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