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Equivalence of the 3-month and 28-day formulations of triptorelin with regard to achievement and maintenance of medical castration in women with endometriosis 

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Presentation on theme: "Equivalence of the 3-month and 28-day formulations of triptorelin with regard to achievement and maintenance of medical castration in women with endometriosis "— Presentation transcript:

1 Equivalence of the 3-month and 28-day formulations of triptorelin with regard to achievement and maintenance of medical castration in women with endometriosis  Jacques Donnez, M.D., Ph.D., Paul J Dewart, M.D., Bernard Hedon, M.D., Antonio Perino, M.D., Adolf E Schindler, M.D., Joëlle Blumberg, M.D., Denis Querleu, M.D.  Fertility and Sterility  Volume 81, Issue 2, Pages (February 2004) DOI: /j.fertnstert

2 FIGURE 1 (A) FSH, (B) LH, and (C) estradiol log linear scale plasma profiles in the two treatment groups (♦ SR 3-month; • SR 28-day). Donnez. Decapeptyl pharmacodynamics in endometriosis. Fertil Steril 2004. Fertility and Sterility  , DOI: ( /j.fertnstert )

3 FIGURE 2 Mean triptorelin ± SD concentration over time following a single IM injection of triptorelin 3-month SR (• Group A) and following three monthly IM injections of triptorelin 28-day SR (○ Group B). Donnez. Decapeptyl pharmacodynamics in endometriosis. Fertil Steril 2004. Fertility and Sterility  , DOI: ( /j.fertnstert )


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