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Volume 139, Issue 2, Pages (August 2010)

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Presentation on theme: "Volume 139, Issue 2, Pages (August 2010)"— Presentation transcript:

1 Volume 139, Issue 2, Pages 377-379 (August 2010)
Inhibition of Transient Lower Esophageal Sphincter Relaxation in GERD: Will Lesogaberan Advance the Field?  Gary W. Falk  Gastroenterology  Volume 139, Issue 2, Pages (August 2010) DOI: /j.gastro Copyright © 2010 AGA Institute Terms and Conditions

2 Figure 1 Vagal pathways involved in TLESR. The sites where GABAB receptors are located are highlighted. LES, lower esophageal sphincter; DVN, dorsal vagal nuclei; NTS, nucleus tractus solitarius. Adapted from Blackshaw LA. Receptors and transmission in the brain-gut axis: potential for novel therapies. IV. GABA(B) receptors in the brain-gastroesophageal axis. Am J Physiol Gastrointest Liver Physiol 2001;281:G311–315. Used with permission of the American Physiology Society. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions


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