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LEOPARD syndrome: a new polyaneurysm association and an update on the molecular genetics of the disease  Marineh Yagubyan, MD, Jean M Panneton, MD, Noralane.

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Presentation on theme: "LEOPARD syndrome: a new polyaneurysm association and an update on the molecular genetics of the disease  Marineh Yagubyan, MD, Jean M Panneton, MD, Noralane."— Presentation transcript:

1 LEOPARD syndrome: a new polyaneurysm association and an update on the molecular genetics of the disease  Marineh Yagubyan, MD, Jean M Panneton, MD, Noralane M Lindor, MD, Emanuela Conti, MD, Anna Sarkozy, MD, Antonio Pizzuti, MD, PhD  Journal of Vascular Surgery  Volume 39, Issue 4, Pages (April 2004) DOI: /j.jvs

2 Fig 1 A, Recurrent irregular-shaped right brachioradial artery aneurysm at presentation. Radial branch had been ligated at initial repair. B, Saccular aneurysm of the left brachial artery at presentation. Note normal ulnar branch. C, Intraoperative image of left brachial aneurysm at initial repair. D, Polytetrafluoroethylene sleeve reinforcement of saphenous vein graft to the ulnar artery at third repair. Journal of Vascular Surgery  , DOI: ( /j.jvs )

3 Fig 2 A, Angiogram of right hand demonstrates multiple digital artery occlusions and an aneurysm overlying the second metacarpal head (arrowhead). B, Angiogram of left periscapular area shows aneurysms supplied by the subscapular and lateral circumflex humeral arteries (arrowheads). C, Fusiform aneurysms in the distribution of the right internal iliac artery (arrowheads). D, Irregularity and aneurysms of the geniculate branches of the right popliteal artery and subtle changes on the left (arrowheads). Journal of Vascular Surgery  , DOI: ( /j.jvs )

4 Fig 3 Lentigines and hypertelorism apparent on facial photograph.
Journal of Vascular Surgery  , DOI: ( /j.jvs )

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