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Correlation between FMISO-PET based hypoxia in the primary tumour and in lymph node metastases in locally advanced HNSCC patients  Anna Bandurska-Luque,

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Presentation on theme: "Correlation between FMISO-PET based hypoxia in the primary tumour and in lymph node metastases in locally advanced HNSCC patients  Anna Bandurska-Luque,"— Presentation transcript:

1 Correlation between FMISO-PET based hypoxia in the primary tumour and in lymph node metastases in locally advanced HNSCC patients  Anna Bandurska-Luque, Steffen Löck, Robert Haase, Christian Richter, Klaus Zöphel, Rosalind Perrin, Steffen Appold, Mechthild Krause, Jörg Steinbach, Jörg Kotzerke, Frank Hofheinz, Daniel Zips, Michael Baumann, Esther G.C. Troost  Clinical and Translational Radiation Oncology  Volume 15, Pages (February 2019) DOI: /j.ctro Copyright © Terms and Conditions

2 Fig. 1 Scatterplots showing the correlation between FMISO uptake in the primary tumour and in lymph node metastases in 15 patients with large lymph node metastases (>5 ml on FDG-PET/CT) at four time-points before and during treatment. The Spearman correlation coefficient ρ significantly differed from 0 prior to and in week 2 and 5 of treatment (TBRpeak – tumour to background peak). Clinical and Translational Radiation Oncology  , DOI: ( /j.ctro ) Copyright © Terms and Conditions

3 Fig. 2 Scatterplot showing the correlation between FMISO uptake in the primary tumour and in lymph node metastases in all assessed patients before initiation of treatment. The SUVmax values were corrected for partial volume effect according to [26]. The Spearman correlation coefficient ρ significantly differed from zero (p = 0.015). (SUVmax – maximum standardized uptake value, PVE – partial volume effect). Clinical and Translational Radiation Oncology  , DOI: ( /j.ctro ) Copyright © Terms and Conditions


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