1. Increased expression levels of CHIT1 in the patients with IPF where they correlate inversely with SMAD7.
Increased expression levels of CHIT1 in the patients with IPF where they correlate inversely with SMAD7. (A) Real-time qRT-PCR evaluations on the expression levels of CHIT1 in whole-lung lysates from normal controls and IPF patients. (B) A scatter plot with regression analysis demonstrating inverse relationship between the levels of CHIT1 and SMAD7 expression in the lungs of IPF patients (Spearman rank test, P = 0.04). (C, D) qRT-PCR evaluations on CHIT1 and SMAD7 expression in alveolar epithelial cells (alveolar type 1 epithelial cells [AT1] and alveolar type 2 epithelial cells [AT2]) isolated from the lungs of normal controls and IPF patients. (E) A scatter plot with regression analysis demonstrating inverse relationship between the levels of CHIT1 and SMAD7 in alveolar epithelial cells isolated from the lungs of IPF patients (P = 0.036, Spearman’s rank test).
Chang-Min Lee et al. LSA 2019;2:e
© 2019 Lee et al.