1. Diabetes and Pregnancy
Robbie Lindsay
BHF Glasgow Cardiovascular Research Centre

2. Per annum
15,000 deliveries
67 women with T1DM
53 T2DM
(0.8% of deliveries in 2015)
~2500 OGTT’s per annum

3. Pregnancy in women with T1DM and T2DM are high risk

4. Pregnancy in women with T1DM and T2DM is high risk

5. Pre pregnancy planning in type 1 and type 2 diabetes
folic acid
HbA1c control
at risk medications
statins
ACE ARB
complications
Bell et al Diabetologia

6. Can we help women prepare for pregnancy better?

8. General obstetric population in GG&C 24% of women BMI>30 at booking
0.8% BMI over 45
10.6% Family history diabetes
1.2% previous GDM
13.3% at risk ethnicity

9. Follow up Mothers
Age 43.6 years
10.7% T2DM vs 1.6%
41.5% IFG or IGT vs 18.4%
Mothers with
Fasting ≥5.1 OR
1 hour ≥10.0 OR =14.3%
2 hour ≥8.5 mmol/l BMI 29.7
age 31.9 years
fasting 4.9
1h 9.6
2 hour 7.7 mmol/l
Follow up Children
Age 11.5 years
Obese % vs 9.9 %
Overweight vs 18.7%
IGT 10.6% vs 5.0%

12. Better counselling before pregnancy
Better detection GDM in pregnancy
Better prevention T2DM after pregnancy