1. Figure 1. Observed mean (SD) micafungin plasma concentrations.
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J Antimicrob Chemother, Volume 74, Issue 4, 15 January 2019, Pages 978–985,
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2. Figure 2. PcVPC for the final PK model of micafungin, based on n = 1000 simulations. Prediction-corrected simulated ...
Figure 2. PcVPC for the final PK model of micafungin, based on n = 1000 simulations. Prediction-corrected simulated (shaded areas) and observed (circles and lines) micafungin concentrations versus time after dose. The solid line connects the median values per bin. The outer dashed lines connect the 5th and 95th percentiles of the observations. The shaded areas are the 95% CI of the 5th and 95th percentile and the median. The vertical tick marks at the top of the graph indicate the placement of the bins.
Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (
J Antimicrob Chemother, Volume 74, Issue 4, 15 January 2019, Pages 978–985,
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3. Figure 3. PTA versus body weight on day 1 (left panel) and in steady-state on day 7 (right panel) for four different ...
Figure 3. PTA versus body weight on day 1 (left panel) and in steady-state on day 7 (right panel) for four different MICs. The horizontal red dotted line represents a PTA of 90%. The shade around the lines represents the 95% CI of the prediction.
Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (
J Antimicrob Chemother, Volume 74, Issue 4, 15 January 2019, Pages 978–985,
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4. Figure 4. Recommendations for maintenance dose by body weight and MICs
Figure 4. Recommendations for maintenance dose by body weight and MICs. This figure appears in colour in the online ...
Figure 4. Recommendations for maintenance dose by body weight and MICs. This figure appears in colour in the online version of JAC and in black and white in the print version of JAC.
Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (
J Antimicrob Chemother, Volume 74, Issue 4, 15 January 2019, Pages 978–985,
The content of this slide may be subject to copyright: please see the slide notes for details.