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Preimplantation genetic diagnosis for Zellweger syndrome

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Presentation on theme: "Preimplantation genetic diagnosis for Zellweger syndrome"— Presentation transcript:

1 Preimplantation genetic diagnosis for Zellweger syndrome
Moeen Al-Sayed, M.D., Saad Al-Hassan, M.D., Mohamed Rashed, Ph.D., Meshal Qeba, B.Sc., Serdar Coskun, D.V.M., Ph.D.  Fertility and Sterility  Volume 87, Issue 6, Pages 1468.e e3 (June 2007) DOI: /j.fertnstert Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

2 FIGURE 1 Examples of normal and mutated sequences of the PEX26 gene from the MDA product obtained from single blastomeres. The mutation was the substitution of guanidine (G, upper) by the adenine (A, below) at nucleotide 296 in the complementary DNA. This mutation in the DNA resulted in a conversion of the tryptophan codon to a stop codon (W99X) in the mRNA. Al-Sayed. PGD for Zellweger syndrome. Fertil Steril 2007. Fertility and Sterility  , 1468.e e3DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions


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