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A. A. Hislop, PhDa, R. R. Lee, MSb, C. G. A. McGregor, MB, FRCSb, S. G

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Presentation on theme: "A. A. Hislop, PhDa, R. R. Lee, MSb, C. G. A. McGregor, MB, FRCSb, S. G"— Presentation transcript:

1 Lung Growth After Transplantation Of An Adult Lobe Of Lung Into A Juvenile Rat 
A.A. Hislop, PhDa, R.R. Lee, MSb, C.G.A. McGregor, MB, FRCSb, S.G. Haworth, FRCP, FACCa  The Journal of Thoracic and Cardiovascular Surgery  Volume 115, Issue 3, Pages (March 1998) DOI: /S (98) Copyright © 1998 Mosby, Inc. Terms and Conditions

2 Fig. 1 Photograph of the right lung (RL) and right cardiac lobe (RCL) of a control rat aged 7.5 months and the recipient right lung (RecRL) and transplanted right cardiac lobe (TxRCL) 6 months after transplantation. Bar = 8.5 mm. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

3 Fig. 2 X-ray film of adult rat with airways imaged after a bronchogram 6 months after transplantation. The right lung is displaced into the left hemithorax. All lobes were inflated with air. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

4 Fig. 3 Photomicrographs of the alveolar region: A, Transplanted right cardiac lobe 6 months after transplantation. B, Recipient right lung 6 months after transplantation. C, Control lung. D, Pneumonectomized lung. a, alveolus; ad, alveolar duct; br, bronchiolus; p, pleura. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

5 Fig. 4 Right lung and right cardiac lobe volume (A) 14 days and (B) 6 months after transplantation and pneumonectomy, together with control values. Mean and standard deviation. *p < 0.01 in comparison with age-matched controls. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

6 Fig. 5 Total alveolar number (A) and alveoli per milliliter (B) in the right lung and right cardiac lobe 6 months after the operation. *p < 0.01 in comparison with control. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

7 Fig. 6 Diameter of lobar bronchus (A) and terminal bronchioli (B) for the right lung and right cardiac lobe 6 months after the operation. *p = 0.05 in comparison with control. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

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