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Coupling to heterotrimers with C-terminal Gα subunit chimeras.

Published byKlaudia Albrecht Modified over 5 years ago

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Presentation on theme: "Coupling to heterotrimers with C-terminal Gα subunit chimeras."— Presentation transcript:

1 Coupling to heterotrimers with C-terminal Gα subunit chimeras.
Coupling to heterotrimers with C-terminal Gα subunit chimeras. Heat maps of ΔBRETmax (normalized to the largest value) for Gs-coupled (Top), Gi-coupled (second row), Gq-coupled (third row), and G12-coupled (Bottom) receptors. Maps are arranged from left to right depending on coupling that is determined more (e.g., H1R) or less (e.g., D1R) by the Gα C terminus (H5.17–H5.26). Each value represents the mean normalized ΔBRETmax from n = 3–6 independent experiments. Najeah Okashah et al. PNAS doi: /pnas ©2019 by National Academy of Sciences

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