1. The Lymphatic System

2. Components Lymphatic vessels Lymphoid organs
 lymph nodes (connect incoming & outgoing lymph vessels)
 spleen
 thymus gland
 red bone marrow

3. Lymphoid organs (a closer look)

4. Functions Collects tissue fluid (lymph) Absorbs fatty acids & glycerol
Defence against disease
 lymph nodes contain macrophages (destroy bacteria & infectious material)

5. Lymphatic Vessels Structurally like veins Have valves
Movement of fluid (lymph) similar to movement in veins

6. Flow of Lymph Fluid RIGHT UPPER BODY
Tissue fluid  Lymphatic capillaries  Lymphatic vessels  Right lymphatic duct  Right subclavian vein  SUPERIOR VENA CAVA
LOWER BODY & UPPER LEFT
Tissue fluid  Lymphatic capillaries  Lymphatic vessels  Thoracic duct  Left subclavian vein  SUPERIOR VENA CAVA

7. Antigens & Antibodies ANTIGEN (foreign substance in your body)
Glycoprotein chain within plasma membrane of foreign substance
Your body recognizes the chain as being “non self”
Examples.
 bacteria
 foreign human cells (transplant tissue)
 cancer cells

8. ANTIBODY
Proteins capable of combining with & neutralizing antigens
Produced by “B Cells” (lymphocytes/ white blood cells)
Secreted into blood & lymph
Recognize antigen because they have receptors on surface that fit like a “lock & key”
Specific antibody for each antigen

9. How they work ANTIBODY + ANTIGEN  INACTIVE (foreign invader) COMPLEX
* Lock & Key fit (like enzymes)… very specific!
AGGLUTINATION: clumped or “agglutinated” antigens

10. Immunity (how your body responds)
Lymphocytes exposed to antigen (naturally or through vaccine)
Manufacture antibodies
Some antibodies remain in lymph nodes forever as memory cells
Capable of producing antibodies during a future invasion of same antigen