1. Serum concentrations of procollagen type I C-peptide (PICP), Fas ligand, osteopontin (OPN) and matrix metalloproteinase (MMP)-7 in healthy controls (HCs) and in patients with idiopathic pulmonary fibrosis (IPF) assessed using a multiplex platform.
Serum concentrations of procollagen type I C-peptide (PICP), Fas ligand, osteopontin (OPN) and matrix metalloproteinase (MMP)-7 in healthy controls (HCs) and in patients with idiopathic pulmonary fibrosis (IPF) assessed using a multiplex platform. Box plot analysis of serum concentrations of a) PICP, b) FasL, c) OPN and d) MMP-7, in HCs (n=100), and in patients with IPF at baseline (n=113), 4 months (n=102) and end of study (EOS) (n=72). One-sided t-test with unequal variance was used to compare analyte concentrations in HCs and patients with IPF for each analyte at each time point. ns: nonsignificant. **: p≤0.01; #: p≤
Yasmina Bauer et al. ERJ Open Res 2017;3:
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