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Subsquamous Extension of Intestinal Metaplasia Is Detected in 98% of Cases of Neoplastic Barrett's Esophagus  Mario Anders, Yasmin Lucks, Muhammad Abbas.

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Presentation on theme: "Subsquamous Extension of Intestinal Metaplasia Is Detected in 98% of Cases of Neoplastic Barrett's Esophagus  Mario Anders, Yasmin Lucks, Muhammad Abbas."— Presentation transcript:

1 Subsquamous Extension of Intestinal Metaplasia Is Detected in 98% of Cases of Neoplastic Barrett's Esophagus  Mario Anders, Yasmin Lucks, Muhammad Abbas El-Masry, Alexander Quaas, Thomas Rösch, Guido Schachschal, Christina Bähr, Ulrich Gauger, Guido Sauter, Jakob R. Izbicki, Andreas H. Marx  Clinical Gastroenterology and Hepatology  Volume 12, Issue 3, Pages (March 2014) DOI: /j.cgh Copyright © 2014 AGA Institute Terms and Conditions

2 Figure 1 Flow sheet showing the course of patients treated for neoplastic BE. Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

3 Figure 2 Scatter plot showing distribution and frequency of SSIM. Subsquamous Barrett's epithelium was seen in 108 patients, ranging from 0.2 mm (minimum) to 9.6 mm (maximum); mean 3.3. Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

4 Figure 3 Schematic drawing of variations in SSIM extent (see text); different extents of Barrett's epithelium underneath squamous epithelium (SSIM) are shown; measurement along the green line does not show any SSIM, while maximum extent of SSIM is depicted by the blue line. C, visible circular BE length; M, total extension of visible BE tongues. Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions

5 Figure 4 Histologic slides of SSIM. (A) The oral extension of BE glands (red arrow) underneath the SQE of the esophagus measures more than 3 mm; H&E 100x. (B) Another case also showing BE extension (red arrow); Alcian blue staining, 200x. (C) Subsquamous extension of a highly differentiated intramucosal Barrett's adenocarcinoma (red arrow); H&E 200x. Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2014 AGA Institute Terms and Conditions


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