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Effectiveness of photodynamic ablation for destruction of endometrial explants in a rat endometriosis model  Alicja A Krzemien, M.D., Dean A Van Vugt,

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Presentation on theme: "Effectiveness of photodynamic ablation for destruction of endometrial explants in a rat endometriosis model  Alicja A Krzemien, M.D., Dean A Van Vugt,"— Presentation transcript:

1 Effectiveness of photodynamic ablation for destruction of endometrial explants in a rat endometriosis model  Alicja A Krzemien, M.D., Dean A Van Vugt, Ph.D., William A Fletcher, M.D., Robert L Reid, M.D.  Fertility and Sterility  Volume 78, Issue 1, Pages (July 2002) DOI: /S (02)

2 FIGURE 1 Histological examination of endometriotic cysts 3 weeks after PDT. (A), A control lesion (ALA, no light) with lush stroma and high columnar epithelium lining the lumen of the cyst. (B), A cystic lesion exposed to systemic ALA and 10 minutes of light treatment, resulting in lasting destruction of endometrial tissues that formed the wall of the cyst. (Stain, hematoxylin-eosin; original magnification, ×6.4) Krzemiem. Photodynamic destruction of endometriosis. Fertil Steril 2002. Fertility and Sterility  , DOI: ( /S (02) )

3 FIGURE 2 Histological assessment of rat abdominal wall 16 days after ALA-PDT, electrosurgery, and resection. (A), Complete reperitonealization and recovery of skeletal muscle were observed after PDT exposure. (B), After bipolar electrosurgery, necrosis and edema of the skeletal muscle was still evident (arrow) with reparative changes. (C), Fibrous tissue and adhesions were present at the site of surgical resection of peritoneum (arrows). P = peritoneal surface. (Stain, hematoxylin-eosin; original magnification, ×6.4). Krzemiem. Photodynamic destruction of endometriosis. Fertil Steril 2002. Fertility and Sterility  , DOI: ( /S (02) )


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